金洪，副研究员
办公室电话：028-85415611
实验室地址：望江校区第一理科楼中518室
邮箱: jinhong@scu.edu.cn
1. 人简介
理学博士，博士后，中国植物保护学会鼠害防治专业委员会委员。先后主持国家重点研发计划项目子课题2项，已发表SCI论文30多篇，其中以第一作者或通讯作者在European Journal of Medicinal Chemistry、Journal of Agricultural and Food Chemistry、Pest Management Science等国际权威SCI杂志上发表10多篇。担任Journal of Agricultural and Food Chemistry、European Journal of Medicinal Chemistry、ACS Sustainable Chemistry & Engineering等SCI杂志审稿人。
2. 研究方向和研究内容：
1、绿色农药的化学与生物学研究
以我国农业病虫害为作用靶标，微生物/植物代谢产物或商业化学农药为先导，创制具有自主知识产权的新型绿色农药；开展微生物/植物代谢产物的分离与纯化，发现新型先导化合物；开展化学农药的合成方法研究。
2、退化草地的生物防治综合配套技术研究
针对草地退化严重、草畜失衡、生产力低效问题，以现有退化草地的生物防治技术为基础，开展鼠虫害监测技术研究；针对不同退化程度草地，开展以生态防治为重点的鼠虫害综合防治技术的研究和示范。
3. 主持和参与项目：
1、“十三五”国家重点研发计划项目子课题，2016YFC0502004-2，退化草地生物综合防治技术和示范，2016.7-2020.12，主持。
2、“十三五”国家重点研发计划项目子课题，2017YFD0200503-4，青藏高原极端微生物菌株的筛选、鉴定及农用代谢产物研究，2017.7-2020.12，主持。
3. 第二次青藏高原综合科学考察研究子专题，2019QZKK040404，生态工程技术评估与绩效管理，2019.11-2024.10，参与。
4. 国家自然科学基金，31272068，几类含呋喃环仿生农药分子结构改造及作用机理研究，2013.1-2016.12，参与。
4. 部分代表性论文:
18. Yongtian Zhao, Qi Wang, Xia Wu, Mingfang Jiang, Hong Jin*, Ke Tao*, Taiping Hou, Unraveling the polypharmacology of a natural antifungal product, eugenol, against Rhizoctonia solani, Pest Management Science, 2021, doi: 10.1002/ps.6400.
17. Yongtian Zhao, Na Yang, Yiming Deng, Ke Tao, Hong Jin*, Taiping Hou, Mechanism of action of novel pyrazole carboxamide containing a diarylamine scaffold against Rhizoctonia solani, Journal of Agricultural and Food Chemistry, 2020, 68, (40), 11068-11076.
16. Jian Yang, Yongtian Zhao, Jun Wan, Mingfang Jiang, Hong Jin*, Ke Tao, Taiping Hou, Synthesis and biological evaluation of novel benodanil-heterocyclic carboxamide hybrids as a potential succinate dehydrogenase inhibitors, Molecules, 2020, 25, 4291.
15. Aigui Zhang, Ying Yue, Jian Yang, Jiaxing Shi, Ke Tao, Hong Jin*, Taiping Hou, Design, synthesis, and antifungal activities of novel aromatic carboxamides containing a diphenylamine scaffold, Journal of Agricultural and Food Chemistry, 2019, 67, (17), 5008-5016.
14. Yuanhang Ren, Jiaxing Shi, Yangping Mu, Ke Tao, Hong Jin*, Taiping Hou, AW1 neuronal cell cytotoxicity: The mode of action of insecticidal fatty acids，Journal of Agricultural and Food Chemistry, 2019, 67, 43, 12129-12136.
13. Aigui Zhang, Ying Yue, Yihua Yang, Jian Yang, Ke Tao, Hong Jin*, Taiping Hou*, Discovery of N-(4-fluoro-2-(phenylamino)phenyl)-pyrazole-4-carboxamide as potential succinate dehydrogenase inhibitors, Pesticide Biochemistry and Physiology, 2019, 158, 175-184.
12. Aigui Zhang, Yihua Yang, Ying Yue, Ke Tao, Taiping Hou*, Hong Jin*, N-[2-[(3-Chlorophenyl)amino]-phenyl]-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide: Synthesis, crystal structure, molecular docking and biological activities, Chemistry & Biodiversity, 2019, 16, e1900118.
11. Yuanhang Ren, Liqin He, Hong Jin*, Ke Tao*, Taiping Hou, Cytotoxicity evaluation and apoptosis-inducing effects of furanone analogues in insect cell line SL2, Food and Agricultural Immunology, 2018, 29, 964-975.
10. Aigui Zhang, Jingya Zhou, Ke Tao, Taiping Hou, Hong Jin*, Design, synthesis and antifungal evaluation of novel pyrazole carboxamides with diarylamines scaffold as potent succinate dehydrogenase inhibitors, Bioorganic & Medicinal Chemistry Letters, 2018, 28, 3042-3045.
9. Xiao-Xiao Zhang, Hong Jin*, Yuan-Jie Deng, Xu-Heng Gao, Yong Li, Yong-Tian Zhao, Ke Tao, Tai-Ping Hou*, Synthesis and biological evaluation of novel pyrazole carboxamide with diarylamine-modified scaffold as potent antifungal agents, Chinese Chemical Letters, 2017, 28, 1731-1736.
8. Hongyu Wang, Xuheng Gao, Xiaoxiao Zhang, Hong Jin*, Ke Tao, Taiping Hou*， Design, synthesis and antifungal activity of novel fenfuram-diarylamine hybrids，Bioorganic & Medicinal Chemistry Letters, 2017, 27(1), 90-93.
7. Hong Jin*, Jingya Zhou, Tao Pu, Aigui Zhang, Xuheng Gao, Ke Tao, Taiping Hou, Synthesis of novel fenfuram-diarylether hybrids as potent succinate dehydrogenase inhibitors, Bioorganic Chemistry, 2017, 73, 76-82.
6. Fang Wen, Hong Jin*, Ke Tao*, Taiping Hou, Design, synthesis and antifungal activity of novel furancarboxamide derivatives, European Journal of Medicinal Chemistry, 2016, 120(2), 244-251.
5. Mingjing Chen, Hong Jin*, Ke Tao, Taiping Hou, Synthesis and bioactivity evaluation of novel benzamide derivatives containing a diphenyl ether moiety, Journal of Pesticide Science, 2014, 39(4): 187-192.
4. Hong Jin, Haoyu Zhao, Feihu Zhao, Shihong Li, Wei Liu, Guoping Zhou, Ke Tao, Taiping Hou*, Efficient epoxidation of chalcones with urea-hydrogen peroxide under ultrasound irradiation, Ultrasonics Sonochemistry, 2009, 16(3), 304-307.
3. Hong Jin, Yucong Geng, Zhiyi Yu, Ke Tao, Taiping Hou*, Lead optimization and anti-plant pathogenic fungi activities of daphneolone analogues from Stellera chamaejasme L., Pesticide Biochemistry and Physiology, 2009, 93(3), 133-137.
2. Hong Jin, Liyu Xiang, Fang Wen, Ke Tao, Qian Liu, Taiping Hou*, Improved synthesis of chalconoid-like compounds under ultrasound irradiation, Ultrasonics Sonochemistry, 2008, 15(5): 681-683.
1. 金洪, 陈鸶, 侯若彤, 王玉良, 陈淑华, 杨志荣. 溴代二羟基二苯醚类化合物的合成与抑菌活性研究, 有机化学, 2006(10), 1424-1428.
5. 部分授权专利:
1. 侯太平，高续恒，金洪，郭聪. 一种草原害鼠的持续性控制方法. 中国发明专利：ZL 201810134602.4.
2. 侯太平，查艳梅，陶科，金洪，岳莹，刘英. 泡盛曲霉菌株及其在农业害虫防治领域的用途. 中国发明专利：ZL 201710204653.5.
3. 侯太平，张肖肖，金洪，陶科. 含二芳胺基的吡唑甲酰胺类化合物及其在农药中的应用. 中国发明专利：ZL 201610019343.1.
